Novel Sites of Adrenomedullin Gene Expression in Mouse and Rat Tissues

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Novel sites of adrenomedullin gene expression in mouse and rat tissues.

Adrenomedullin (AM) was originally identified in pheochromocytoma tissue and was characterized as a hypotensive peptide. The tissue distribution and cellular localization of AM messenger RNA (mRNA) were determined in mouse and rat tissues by in situ hybridization. Three probes were used: two nonoverlapping probes to the pro-AM N-terminal 20 peptide (PAMP) and AM peptide regions of mouse pro-AM,...

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Regulation of Adrenomedullin Gene Expression in the Rat Heart

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ژورنال

عنوان ژورنال: Endocrinology

سال: 1998

ISSN: 0013-7227

DOI: 10.1210/en.139.5.2253